* PHYSICS SEMINAR *
관련링크
본문
" Illuminating and Controlling Membrane Biological
Processes at the Nanoscale
연사: Tae-Young Yoon[University of Illinois at Urbana-Champaign]
일시: 2007 년 2 월 14 일 16:00 ~
장소: 물리학과 세미나실(공학3동201호)
Can biophysical approaches really shed light into the research on membrane biological processes? Are those approaches too simplified to describe the real cellular event? Emerging nano-technology and single-molecule study are fundamentally shaking such a skeptical viewpoint. Structures fabricated at the nanoscale and the novel FRET imaging technique provide a unprecedented avenue for controlling and illuminating membrane biological processes at the innate length scale, the nanometer range. Here I report two novel examples; control of membrane molecule dynamics using nano-topographic structures, and real-time imaging of SNARE protein-driven membrane fusion at the single event level. Taking one step further, I will dissect the previously elusive function of two membrane fusion regulators and then, report the first reconstitution of the core neuron-signaling machinery; Ca2+-triggered synchronized membrane fusion events. This study could demonstrate how biophysical approaches address and answer the contemporary questions that biologists really want to know."
Processes at the Nanoscale
연사: Tae-Young Yoon[University of Illinois at Urbana-Champaign]
일시: 2007 년 2 월 14 일 16:00 ~
장소: 물리학과 세미나실(공학3동201호)
Can biophysical approaches really shed light into the research on membrane biological processes? Are those approaches too simplified to describe the real cellular event? Emerging nano-technology and single-molecule study are fundamentally shaking such a skeptical viewpoint. Structures fabricated at the nanoscale and the novel FRET imaging technique provide a unprecedented avenue for controlling and illuminating membrane biological processes at the innate length scale, the nanometer range. Here I report two novel examples; control of membrane molecule dynamics using nano-topographic structures, and real-time imaging of SNARE protein-driven membrane fusion at the single event level. Taking one step further, I will dissect the previously elusive function of two membrane fusion regulators and then, report the first reconstitution of the core neuron-signaling machinery; Ca2+-triggered synchronized membrane fusion events. This study could demonstrate how biophysical approaches address and answer the contemporary questions that biologists really want to know."
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